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1

PDAPP; YFP double transgenic mice: A tool to study amyloid-β associated changes in axonal, dendritic, and synaptic structures

Robert P. Brendza, Cara O'Brien, Kelly Simmons, Daniel W. McKeel, Kelly R. Bales, Steven M. Paul, John W. Olney, Joshua R. Sanes, David M. Holtzman

Journal:

The Journal of Comparative Neurology

Year:

2003

Language:

english

File:

PDF, 848 KB

english, 2003

2

Posterior Localization of Dynein and Dorsal-Ventral Axis Formation Depend on Kinesin in Drosophila Oocytes

Robert P. Brendza, Laura R. Serbus, William M. Saxton, Joseph B. Duffy

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 248 KB

english, 2002

3

Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design

Lansdon, Eric B., Brendza, Katherine M., Hung, Magdeleine, Wang, Ruth, Mukund, Susmith, Jin, Debi, Birkus, Gabriel, Kutty, Nilima, Liu, Xiaohong

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 3.86 MB

english, 2010

4

E. coli Rep oligomers are required to initiate DNA unwinding in vitro

Wei Cheng, John Hsieh, Katherine M. Brendza, Timothy M. Lohman

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 545 KB

english, 2001

5

Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex

Eric B. Lansdon, Dharmaraj Samuel, Leanna Lagpacan, Katherine M. Brendza, Kirsten L. White, Magdeleine Hung, Xiaohong Liu, Constantine G. Boojamra, Richard L. Mackman, Tomas Cihlar, Adrian S. Ray, Mar

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.50 MB

english, 2010

6

The Macroscopic Rate of Nucleic Acid Translocation by Hepatitis C Virus Helicase NS3h Is Dependent on Both Sugar and Base Moieties

Ali R. Khaki, Cassandra Field, Shuja Malik, Anita Niedziela-Majka, Stephanie A. Leavitt, Ruth Wang, Magdeleine Hung, Roman Sakowicz, Katherine M. Brendza, Christopher J. Fischer

Journal:

Journal of Molecular Biology

Year:

2010

Language:

english

File:

PDF, 1.71 MB

english, 2010

7

Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV

Todd C. Appleby, Robert Anderson, Olga Fedorova, Anna M. Pyle, Ruth Wang, Xiaohong Liu, Katherine M. Brendza, John R. Somoza

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

8

Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition

Sheng-Kwei Song, Joong Hee Kim, Shiow-Jiuan Lin, Robert P. Brendza, David M. Holtzman

Journal:

Neurobiology of Disease

Year:

2004

Language:

english

File:

PDF, 471 KB

english, 2004

9

Use of YFP to study amyloid-β associated neurite alterations in live brain slices

Robert P. Brendza, Kelly Simmons, Kelly R. Bales, Steven M. Paul, Mark P. Goldberg, David M. Holtzman

Journal:

Neurobiology of Aging

Year:

2003

Language:

english

File:

PDF, 380 KB

english, 2003

10

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice

Ronald B DeMattos, Robert P Brendza, John E Heuser, Malca Kierson, John R Cirrito, John Fryer, Patrick M Sullivan, Anne M Fagan, Xianlin Han, David M Holtzman

Journal:

Neurochemistry International

Year:

2001

Language:

english

File:

PDF, 688 KB

english, 2001

11

P2-063 In vivo dynamics of amyloid associated neuritic dystrophy before and after anti-Aβ immunotherapy

Robert P. Brendza, Brian J. Bacskai, Kelly A. Simmons, Jesse M. Skoch, William E. Klunk, Chester A. Mathis, Kelly R. Bales, Steven M. Paul, David M. Holtzman

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 317 KB

english, 2004

12

RNase H Active Site Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Design, Biochemical Activity, and Structural Information

Kirschberg, Thorsten A., Balakrishnan, Mini, Squires, Neil H., Barnes, Tiffany, Brendza, Katherine M., Chen, Xiaowu, Eisenberg, Eugene J., Jin, Weili, Kutty, Nilima, Leavitt, Stephanie, Liclican, Albe

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.23 MB

english, 2009

13

A comparison of conventional versus push-pull microdialysis for the detection of amyloid β in the mouse brain

Ruth Motter, Isaac Veinbergs, Thomas Cremers, Marieke Van der Hart, Lisa Yu, Harm Kooijker, Gunnar Flik, Robert Freije, Robert Brendza, Pearl Tanaka

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 57 KB

english, 2011

14

10.1038/85487

Han, Byung Hee, DeMattos, Ronald B., Dugan, Laura L., Kim-Han, Jeong Sook, Brendza, Robert P., Fryer, John D., Kierson, Malca, Cirrito, John, Quick, Kevin, Harmony, Judith A. K., Aronow, Bruce J., Hol

Journal:

Nature Medicine

Year:

2001

Language:

english

File:

PDF, 4.14 MB

english, 2001

15

Nucleic Acid Translocation By Hepatitis C Virus Helicase NS3h Is Dependent on Sugar and Base Moieties

Fischer, Christopher J., Khaki, Ali R., Field, Cassandra, Malik, Shuja, Wang, Ruth, Niedziela-Majka, Anita, Leavitt, Stephanie, Hung, Magdeleine, Sakowicz, Roman, Brendza, Katherine M.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

16

Lipid Sensing Apolipoprotein A-I for Novel High-Throughput Lipidation Assays

Niedziela-Majka, Anita, Lad, Latesh, Chishom, Jeffrey W., Lagpacan, Leanna, Schwartz, Karen, Hung, Magdeleine, Jin, Debi, Fung, Wanchi, Brendza, Katherine M., Liu, Xioahong, Pagratis, Nikos, Sakowicz,

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

17

Personality Assessment Inventory predictors of therapeutic success or failure in chronic headache patients

D. Brendza, K. Ashton, A. Windover, M. Stillman

Journal:

The Journal of Pain

Year:

2005

Language:

english

File:

PDF, 45 KB

english, 2005

18

Three Routes to Suppression of the Neurodegenerative Phenotypes Caused by Kinesin Heavy Chain Mutations

Djagaeva, I., Rose, D. J., Lim, A., Venter, C. E., Brendza, K. M., Moua, P., Saxton, W. M.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.78 MB

english, 2012

19

A Function for Kinesin I in the Posterior Transport of oskar mRNA and Staufen Protein

Journal:

Year:

2000

Language:

english

File:

PDF, 422 KB

english, 2000

20

Microtubule−Kinesin Interface Mutants Reveal a Site Critical for Communication †

Klumpp, Lisa M., Brendza, Katherine M., Gatial, Joseph E., Hoenger, Andreas, Saxton, William M., Gilbert, Susan P.

Journal:

Year:

2004

Language:

english

File:

PDF, 588 KB

english, 2004

21

Motor Domain Mutation Traps Kinesin as a Microtubule Rigor Complex †

Klumpp, Lisa M., Brendza, Katherine M., Rosenberg, John M., Hoenger, Andreas, Gilbert, Susan P.

Journal:

Year:

2003

Language:

english

File:

PDF, 825 KB

english, 2003

22

Defining the Role of Phosphomethylethanolamine N -Methyltransferase from Caenorhabditis elegans in Phosphocholine Biosynthesis by Biochemical and Kinetic Analysis †

Palavalli, Lavanya H., Brendza, Katherine M., Haakenson, William, Cahoon, Rebecca E., McLaird, Merry, Hicks, Leslie M., McCarter, James P., Williams, D. Jeremy, Hresko, Michelle C., Jez, Joseph M.

Journal:

Year:

2006

Language:

english

File:

PDF, 420 KB

english, 2006

23

Dithiothreitol Causes HIV-1 Integrase Dimer Dissociation While Agents Interacting With the Integrase Dimer Interface Promote Dimer Formation

Tsiang, Manuel, Jones, Gregg S., Hung, Magdeleine, Samuel, Dharmaraj, Novikov, Nikolai, Mukund, Susmith, Brendza, Katherine M., Niedziela-Majka, Anita, Jin, Debi, Liu, Xiaohong, Mitchell, Michael, Sak

Journal:

Year:

2011

Language:

english

File:

PDF, 2.59 MB

english, 2011

24

Lethal Kinesin Mutations Reveal Amino Acids Important for ATPase Activation and Structural Coupling

Brendza, K. M., Rose, D. J., Gilbert, S. P., Saxton, W. M.

Journal:

Journal of Biological Chemistry

Year:

1999

Language:

english

File:

PDF, 1.15 MB

english, 1999

25

Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain

Brendza, K. M., Cheng, W., Fischer, C. J., Chesnik, M. A., Niedziela-Majka, A., Lohman, T. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 624 KB

english, 2005

26

Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid- Peptide, Partial Restoration via -Secretase Inhibition

Han, B. H., Zhou, M.-l., Abousaleh, F., Brendza, R. P., Dietrich, H. H., Koenigsknecht-Talboo, J., Cirrito, J. R., Milner, E., Holtzman, D. M., Zipfel, G. J.

Journal:

Journal of Neuroscience

Year:

2008

Language:

english

File:

PDF, 447 KB

english, 2008

27

The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

Cheng, W., Brendza, K. M., Gauss, G. H., Korolev, S., Waksman, G., Lohman, T. M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 398 KB

english, 2002

28

Clonal Tests of Conventional Kinesin Function during Cell Proliferation and Differentiation

Brendza, R. P., Sheehan, K. B., Turner, F.R., Saxton, W. M.

Journal:

Molecular Biology of the Cell

Year:

2000

Language:

english

File:

PDF, 1.29 MB

english, 2000

29

A Kinesin Mutation That Uncouples Motor Domains and Desensitizes the -Phosphate Sensor

Brendza, K. M., Sontag, C. A., Saxton, W. M., Gilbert, S. P.

Journal:

Journal of Biological Chemistry

Year:

2000

Language:

english

File:

PDF, 966 KB

english, 2000

30

Lipid-Sensing High-Throughput ApoA-I Assays

Niedziela-Majka, A., Lad, L., Chisholm, J. W., Lagpacan, L., Schwartz, K., Hung, M., Jin, D., Fung, W., Brendza, K. M., Liu, X., Pagratis, N., Sakowicz, R.

Journal:

Journal of Biomolecular Screening

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

31

Intraintestinal Carbohydrate in Rats during the Feeding of Glucose or of Raw or Cooked Cornstarch

Malik, M. A., Trout, D. L., Emamali, B. C., Brendza, D. J.

Journal:

Experimental Biology and Medicine

Year:

1982

Language:

english

File:

PDF, 542 KB

english, 1982

32

GS-5806 Inhibits Pre- to Postfusion Conformational Changes of the Respiratory Syncytial Virus Fusion Protein

Samuel, Dharmaraj, Xing, Weimei, Niedziela-Majka, Anita, Wong, Jinny S., Hung, Magdeleine, Brendza, Katherine M., Perron, Michel, Jordan, Robert, Sperandio, David, Liu, Xiaohong, Mackman, Richard, Sak

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

File:

PDF, 542 KB

2015

33

Role of apoE/Aβ interactions in Alzheimer’s disease: insights from transgenic mouse models

Brendza, R P, Bales, K R, Paul, S M, Holtzman, D M

Journal:

Molecular Psychiatry

Year:

2002

Language:

english

File:

PDF, 213 KB

english, 2002

34

GS-5806 Inhibits Pre- to Postfusion Conformational Changes of the Respiratory Syncytial Virus Fusion Protein

Samuel, Dharmaraj, Xing, Weimei, Niedziela-Majka, Anita, Wong, Jinny S., Hung, Magdeleine, Brendza, Katherine M., Perron, Michel, Jordan, Robert, Sperandio, David, Liu, Xiaohong, Mackman, Richard, Sak

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 542 KB

english, 2015

35

Amyloid-?? Immunotherapies in Mice and Men

Brendza, Robert P., Holtzman, David M.

Journal:

Alzheimer Disease & Associated Disorders

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

36

Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement

Lee, Seung-Hye, Le Pichon, Claire E., Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded, Chan, Ruby, Ernst, James A., DiCara, Danie

Journal:

Year:

2016

Language:

english

File:

PDF, 3.79 MB

english, 2016

37

Phosphoethanolamine N -methyltransferase (PMT-1) catalyses the first reaction of a new pathway for phosphocholine biosynthesis in Caenorhabditis elegans

Brendza, Katherine M., Haakenson, William, Cahoon, Rebecca E., Hicks, Leslie M., Palavalli, Lavanya H., Chiapelli, Brandi J., McLaird, Merry, McCarter, James P., Williams, D. Jeremy, Hresko, Michelle

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 911 KB

english, 2007

38

Tau antibodies lacking effector function minimize inflammatory responses while effectively blocking spread of tau pathology

Lee, Seung-Hye, Le Pichon, Claire, Adolfsson, Oskar, Gafner, Valérie, Pihlgren, Maria, Lin, Han, Solanoy, Hilda, Brendza, Robert, Ngu, Hai, Foreman, Oded, Chan, Ruby, Ernst, James, Dicara, Danielle, H

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

39

Micro-CT imaging and structural analysis of glomeruli in a model of Adriamycin-induced nephropathy

Xie, Luke, Koukos, Georgios, Barck, Kai, Foreman, Oded, Lee, Wyne P, Brendza, Robert, Eastham-Anderson, Jeff, McKenzie, Brent S, Peterson, Andrew, Carano, Richard A. D.

Journal:

American journal of physiology. Renal physiology

Year:

2018

Language:

english

File:

PDF, 10.85 MB

english, 2018

40

Biochemical characterization of tirabrutinib and other irreversible inhibitors of Bruton's tyrosine kinase reveals differences in on - and off - target inhibition

Liclican, Albert, Serafini, Loredana, Xing, Weimei, Czerwieniec, Gregg, Steiner, Bart, Wang, Ting, Brendza, Katherine M., Lutz, Justin D., Keegan, Kathleen S., Ray, Adrian S., Schultz, Brian E., Sakow

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2020

File:

PDF, 1.28 MB

2020

41

Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS

Dominguez, Sara, Varfolomeev, Eugene, Brendza, Robert, Stark, Kim, Tea, Joy, Imperio, Jose, Ngu, Hai, Earr, Timothy, Foreman, Oded, Webster, Joshua D., Easton, Amy, Vucic, Domagoj, Bingol, Baris

Journal:

Cell Death & Differentiation

Year:

2020

File:

PDF, 4.39 MB

2020